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Associate ProfessorPrincipal Investigator
Center for Sleep and Cognition, Department of Medicine, Yong Loo Lin School of Medicine Center for Translational Magnetic Resonance Research, Yong Loo Lin School of Medicine Neuroscience and Behavioral Disorders Program, Duke-National University of Singapore Medical School National University of Singapore Deputy Director Center for Translational Magnetic Resonance Research, Yong Loo Lin School of Medicine, National University of Singapore Office: Tahir Foundation Building (MD1) 12 Science Drive 2, #13-05C National University of Singapore Singapore 117549 Phone: +65 6601 4918 Email: [email protected] |
Dr. Juan (Helen) Zhou is an Associate Professor and Principal Investigator of the Multimodal Neuroimaging in Neuropsychiatric Disorders Laboratory in the Center for Sleep and Cognition, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore (NUS). She also holds a joint appointment with Neuroscience and Behavioral Disorders Program at Duke-National University of Singapore Medical School, Singapore. Dr. Zhou serves as the Deputy Director, Center for Translational Magnetic Resonance Research MR operations at Yong Loo Lin School of Medicine. Her research focuses on the network-based vulnerability hypothesis in disease. Her lab studies the human neural bases of cognitive functions and the associated vulnerability patterns in aging and neuropsychiatric disorders using multimodal neuroimaging methods, psychophysical techniques, and machine learning approaches. Prior to joining NUS in 2011, Helen was an associate research scientist in the Department of Child and Adolescent Psychiatry (New York University). She did a two-year post-doctoral fellowship at the Memory and Aging Centre (Department of Neurology, University of California, San Francisco), from 2008 to 2010. Helen received her Bachelor degree in Computer Science with first class honour (First class, 3.5 years accelerated) in 2003 and her Ph.D. in Neuroimaging in 2008 from Nanyang Technological University, Singapore. She is the recipient of undergraduate scholarship from Ministry of Education, Singapore (1998-2003) and the nominee for Lee Kuan Yew Gold Medal and the Institution of Engineers Singapore Gold Medal, Singapore in 2004. Helen has published in a number of journals such as Neuron, Brain, PNAS, Neurology, NeuroImage, and Molecular Psychiatry and has been the recipient of research support from National Medical Research Council and Biomedical Research Council, Singapore as well as the Royal Society, UK. She serves as reviewers and editors for a number of journals (NeuroImage, Human Brain Mapping, Communications Biology) and grants. She is the Council – Secretary and Program Committee Member of the Organization for Human Brain Mapping. She is a member of the Organization for Human Brain Mapping, Society for Neuroscience, International Society to Advance Alzheimer’s Research and Treatment, International Society of Magnetic Resonance in Medicine, and American Academy of Neurology. For more information, visit Dr. Zhou's Google Scholar page. |
Senior research fellows
My current research is on the brain functional and structural changes associated with healthy ageing, especially on the functional connectomic changes during rest and task.
As a Post-doc, I am responsible for designing experiments and conducting multimodal data analysis based on EEG and fMRI. I also have a general interest in applied statistical methods for behavioral and neuroimaging data. I was trained as a cognitive psychologist when I pursued my PhD in NUS. Email: [email protected] |
I'm currently involved in projects studying brain functional and structural development underlying individual differences in young population, including typical developing adolescents, individuals at ultra-high risk for psychosis, and children with ADHD and ASDC.
As a research fellow in Dr. Zhou's lab, I am responsible for designing psychological experiments, performing neuroimaging research using EEG, fMRI and DTI, and exploring the application of new imaging methods to our research. My research interest is in the neural basis of human cognition and memory. I did my PhD at the psychology department in the National University of Singapore. Email: [email protected] |
My current research projects include the functional and structural brain changes associated with attention deficit hyperactivity disorder and autism spectrum disorder, systemic lupus erythematosus in adults, and dementia in aging. I am also involved in the test-retest reliability studies of brain functional connectivity measures derived from different scanning sequences and paradigms.
As a research fellow in Dr. Zhou's lab, my other responsibility includes the management of IT staffs in the lab. I got my PhD degree in Tsinghua University and my thesis was on the brain stimulation related intracranial recording. Email: [email protected] |
research fellows
As a Post-doc, I am responsible for the development and application of advanced diffusion MRI models for the purpose of isolating the complex pathologies in the mixed neurodegenerative and vascular disease. These methods could help to develop non-invasive biomarkers for differential diagnosis and disease monitoring.
I obtained my PhD in Integrated Biology and Medicine at Duke-NUS (Singapore). My PhD research work focused on examining the spatiotemporal cascade of neuropathological events in dementia progression using multimodal neuroimaging assays such as magnetic resonance imaging (MRI), functional brain MRI, and diffusion tensor imaging (DTI). Email: [email protected] |
As a research fellow at Dr Helen Zhou's lab, I am involved in projects examining the influence of age and various disease pathologies (such as cerebrovascular disease, amyloid-β and tau) on cross-sectional and longitudinal functional and structural brain changes. The long-term goal of my research is to advance knowledge on the brain mechanisms underlying age-related and pathological-related cognitive decline, as well as to develop non-invasive biomarkers to detect early brain changes and predict future cognitive decline and neurodegeneration in elderly individuals.
I recently received my PhD in Integrated Biology and Medicine at Duke-NUS Medical School, also under the supervision of Dr Zhou. For my PhD thesis, I investigated the differential effects of Alzheimer's disease and cerebrovascular disease on brain functional and structural network changes. In addition, I applied advanced functional connectivity measures to examine ageing-related functional network organization changes in elderly individuals. Email: [email protected] |
Affiliated Research / ClinicaL fellows
As a MD-PhD graduate from Duke-NUS, I am interested in the study of longitudinal brain changes using multimodal neuroimaging techniques. Currently, I am also helping in projects of developing imaging biomarkers to diagnose psychiatric conditions.
I graduated with B. Chem Eng from NUS. Neuroscience is one of the fastest growing area in medicine and there are still lot of questions to be answered. I am very excited about coming research opportunities in our lab. Email: [email protected] |
I am a visiting fellow and collaborate with Helen Zhou's lab on various projects, including morphometry and connectivity analyses on subjects with schizophrenia, bipolar disorder, and ADHD.
I obtained my Ph.D. in Pharmacology from the National University of Singapore and did my postdoctoral training under the Psychiatric Neuroimaging and Schizophrenia Clinical and Research Programs, Massachusetts General Hospital; Harvard Medical School. Email: [email protected] |
Research Associates
I am involved in projects related to functional and structural brain changes associated with motor and cognitive impairment following stroke. My research interests lie in the effects and mechanisms of stroke neurorehabilitation.
I worked with Dr. Helen Zhou on my PhD thesis by investigating how brain functional and structural changes reflect motor recovery and cognitive decline in stroke using functional magnetic resonance imaging, diffusion tensor imaging, and T1-weighted images. I obtained my bachelor's and master's degree in Occupational Therapy from the National Taiwan University, Taiwan. I enjoy running, watching movies, and traveling as leisure. Oh, I am a foodie as well Email: [email protected] |
“Never do things others can do and will do if there are things others cannot do or will not do.” - Amelia Earhart Research epitomizes this philosophy, allowing me to transform my degree into a practical tool capable of making real life impact. As an IT research assistant, I hope to hone my technical skills, exploring how they can develop better diagnostic tools that facilitate early interventions whilst reducing the complexities of comorbidity for neuropsychiatric disorders.
In my free time, I like to immerse myself in activities relating to sports, music and literature. Email: [email protected] |
Research Assistants
After completing an internship with Dr Zhou's lab, I deepened my interest in understanding the biological underpinnings of ageing and psychiatric disorders. At the same time, I picked up some programming knowledge and used it as part of my undergraduate honours thesis. Now that I have returned to the lab as an RA, I wish to delve deeper into the complexities of neuroimaging and possibly further my studies in cognitive neuroscience in future.
Beyond work, I like to exercise frequently and particularly enjoy rock climbing. I also watch anime and read manga in my free time. Email: [email protected] |
I graduated from the National University of Singapore as a major in Psychology.
I am currently an RA at the lab. I am interested in computational methods that predict neurodegeneration in disease. In my free time, I like to sing and read. Email: [email protected] |
COLLABORATING Research Assistant
I graduated with a degree in Biomedical Science, and am particularly interested in identifying potential biomarkers in neurodegenerative and psychiatric disorders.
After graduation, I worked as a research assistant and was involved in measuring peripheral inflammatory and oxidative stress biomarkers in department of medicine, division of neurology, NUS. Following this, I hope to learn more about imaging genetics and explore the relationship between brain structure/function and gene expression. As a research assistant in this lab, my main role is to look at potential biomarkers in CSF and blood as well as their associations with imaging measures in dementia. In my spare time, I like to watch movies and play the piano. Email: [email protected] |
ph.d. / m.d. students
I graduated with a Bachelor degree from Sun Yat-sen University in National Information Management in 2017. I did my undergraduate thesis in Computational Affective Neuroscience Lab of Sun Yat-sen University, and continued as a Research Assistant.
Currently, I am a Duke-NUS IBB (Integrated Biostatistics and Bioinformatics) PhD student under Dr. Helen Zhou, and I am interested in using multimodal neuroimaging and machine learning analysis to develop effective diagnostic/prognostic biomarkers in neuropsychiatric disorders. In my spare time, I enjoy listening to various genres of music and traveling. Email: [email protected] |
I graduated with a B.Sc. (Hons) in Biological Sciences under the multidisciplinary research-oriented CN Yang Scholars' Programme in Nanyang Technological University. Currently, I am a NGS PhD student under Dr Thomas Yeo and Dr Helen Zhou.
I am interested in combining the knowledge from neurobiology and neuroimaging to gain a more holistic perspective of the human brain. I am particularly interested in memory, thoughts and dreams and their representations in our brains, and how these can differ in aging and in disease. My hobbies include reading, watching psychological thrillers and listening to music. Currently, I am also learning Japanese. Email: [email protected] |
I'm a neurologist at National University Hospital who subspecialises in behavioural neurology. I am interested in cognitive and theoretical neuroscience, and the application of models to explain cognitive deterioration in dementia.
In my free time, I read eclectically. Email: [email protected] |
I completed my bachelor's degree in Electrical Engineering from the University of Sydney in 2020.
Currently, I am a PhD student at Yong Loo Lin School of Medicine, under the supervision of Professor Helen Zhou. My research topic is Multimodal Neuroimaging in Neuropsychiatric Disorders. I am especially interested in combining knowledge in machine learning and neuroscience, and performing analysis on fMRI/EEG data. In my spare time, I enjoy petting my cat, reading and traveling. I am especially an outdoor person. I love diving and hiking from time to time. Email: [email protected] |
I graduated with a B.Sc. (Hons) in Biological Sciences under the CN Yang Scholars' Programme in Nanyang Technological University in 2019.
I am interested in using multimodal neuroimaging to investigate the changes in structural and functional brain networks associated with neuropsychiatric disorders, in particular dementia. In my spare time, I enjoy reading and solving puzzles. Email: [email protected] |
Joint ph.d. / master's students
I obtained my Bachelor's degree in Electrical and Electronic Engineering from Nanyang Technological University.
Currently, I am a PhD candidate studying with Dr. Jiang Xudong, Dr. Guan Cuntai and Dr. Helen Zhou. My research topic is Machine Learning on Neuroimaging Data in Neuropsychiatric Disorders. Thus it is an interdisciplinary study which combines engineering and neuroscience. I work on computational algorithms which extract the feature of the MRI/fMRI/DTI data and perform further analysis on them. I enjoy learning languages and painting. I learned Japanese, Korean and German. Though I forget most of the previous one when I start to learn a new language. I like both traditional Chinese painting and pencil drawing. Email: [email protected] |