latest news
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- Our Principal Investigator, Dr. Helen Zhou publised a new book chapter on neurodegeneration online, page 98-122, published by Oxford University Press.
- Our PhD student, Wang Chenhao is featured in Duke-NUS news for his PNAS paper.
- The abstract of our Research Assistant, Ms Tan Yi Jayne titled "Higher Peripheral TREM2 mRNA Expression Levels Are Related to Cognitive Deficits and Hippocampal Atrophy in Alzheimer's Disease and Amnestic MCI" has been accepted for Oral Presentation at the Alzheimer's Association International Conference (AICC) 2016 in Toronto, Canada.
- The abstract of our Research Fellow, Dr Liu Siwei titled "Distinct brain networks underlie individual differences in human spatial working memory capacity" has been accepted for poster presentation at the 22nd Annual Meeting of the Organization for Human Brain Mapping (OHBM) in Geneva, Switzerland.
- The abstracts of our Research Fellow, Dr Qiu Yingwei titled "Inter-hemispheric functional dysconnectivity mediates the effect of corpus callosum degeneration on memory impairment in AD and amnestic MCI" has been accepted for poster presentation at The International Society for Magnetic Resonance in Medicine (ISMRM) 24th Annual Meeting & Exhibition 07-13 May 2016 in Singapore. Also, another abstracts of Dr Qiu titled "The dissociable effects of APOE4 on the hippocampal-cortical memory network and fronto-parietal control network in subjects with cognitive impairment no dementia" has been accepted for poster presentation at the 22nd Annual Meeting of the Organization for Human Brain Mapping (OHBM) in Geneva, Switzerland.
- The abstract of our MD student, Tay Wen Shu, Terence titled "Resting State Functional Magnetic Resonance Imaging Connectivity Changes In Chronic Postsurgical Pain" has been accepted for oral presentation at Australian Pain Society 36th Annual Scientific Meeting.
- The abstracts of our Research Fellow, Dr Eric Ng Kwun-Kei titled "Reduced functional segregation between the default mode network and the executive control network in healthy older adults: a longitudinal study" and our PhD student, Wang Chenhao titled "Fluctuations in Functional Connectivity Predict Shifts in Arousal State" have been accepted for oral presentation at The International Society for Magnetic Resonance in Medicine (ISMRM) 24th Annual Meeting & Exhibition 07-13 May 2016 in Singapore.
NEWS & events
- Between May 9th to 11th, 2016, our lab have a series of meaningful events happening in 24th International Society for Magnetic Resonance in Medicine (ISMRM) annual Meeting and Exhibition, Singapore such as below:
- Our Principal Investigator, Dr. Helen Zhou gave a presentation titled "Network-sensitive structural and functional MR imaging methods"
- Our Research Fellow, Dr. Eric Ng Kwun-Kei gave an oral presentation titled "Reduced functional segregation between the default mode network and the executive control network in healthy older adults: a longitudinal study"
- Our PhD Student, Wang Chenhao gave an oral presentation titled "Fluctuations in functional connectivity predict shifts in arousal state"
- Our PhD Student, Joanna Chong Su Xian gave a poster presentation titled "The influence of cerebrovascular disease on structural covariance networks in prodromal and early stages of alzheimer's disease"
- Our Research Fellows, Dr. Qiu Yingwei and Dr. Cisy Liu gave a poster presentation titled "Inter-hemisphere functional dysconnectivity mediates the effect of corpus callosum degeneration on memory impairment in AD and amnestic MCI"
- Our PhD Student, Ji Fang gave a poster presentation titled "Brain white matter abnormalities in Alzheimer's disease with and without cerebrovascular disease"
- On 29th January 2016, Our Research Fellow Dr. Eric Ng Kwun-Kei gave a research presentation titled "Reduced functional segregation between the default mode network and the executive control network in healthy older adults: a longitudinal study"
- During the period of 18th to 22nd November, Dr. Helen Zhou gave a symposium talk titled "Structural and Functional Abnormalities in Schizophrenia, Bipolar Disorder, and Persons at Risk for Psychosis" at the WPA International Congress of Psychiatry and 4th Asian Congress of Schizophrenia Research in Taipei.
- On the 14th of November, HZ Lab members and CNL members went to ASPIRE55 – Asia's First Virtual Retirement Village (http://www.aspire55.com) to conduct a recruitment drive for two of the projects: Healthy Aging Brain Connectome (HABC) and Singapore Longitudinal Aging Brain Study (SLABS).
- Dr. Helen Zhou gave a presentation on dynamic functional connectivity at the Society for Neuroscience (SfN) annual meeting in Chicago on the 20th October 2015 (session number: 469.13). Particularly, her presentation featured the recent work from our lab by graduate student Chen Hao Wang on arousal-associated dynamic functional connectivity patterns predicting vigilance performance.
- Dr. Cisy Liu presented the poster of our collaboration work with Dr. Christopher Chen and Dr. Carol Cheung on retina-brain association in healthy subjects and patients with cognitive impairment and Alzheimer's disease at the Society for Neuroscience (SfN) annual meeting in Chicago on the 17th October 2015 (session number: 40.05). Using imaging techniques including spectral-domain optical coherence tomography (SD-OCT) and diffusion tensor imaging (DTI), we found that the association between macular ganglion cell - inner plexiform thickness and brain structure integrity in healthy normal subjects is disrupted in patients with cognitive impairment and Alzheimer's disease.
- Dr. Eric Ng presented his poster on impaired gender judgment by irrelevant disgusted expression showed early and mid-latency ERP changes in Organization for Human Brain Mapping (OHBM) 2015 annual meeting in Honolulu, Hawaii. In the study we found that presentation of disgusted expressions affected participants discrimination of the faces depending on the task relevance of the emotion. Using temporospatial PCA we found that this dependence may modulate early and mid-latency ERP components, such as the vertex visual potential (VPP) and the early processing negativity (EPN).
- Assistant Professor Kawin Setsompop from the Martinos Centre for Biomedical Imaging, Harvard Medical School visited our lab in January 2015.
- Our MD/PhD student, Chenhao Wang, presented his poster on reduced functional and structural connectivity of the salience network in persons at-risk for psychosis at the Society for Neuroscience (SfN) annual meeting in Washington DC (15-19 November 2014). This study examined functional and structural connectivity within the salience network in subject at risk for psychosis using a combined task-free fMRI and DTI approaches. We found that reduced SN functional and structural connectivity that supports SN dysconnectivity hypothesis in psychosis.
- Dr. Helen Zhou gave a symposium talk at the Alzheimer's Association International Conference (AAIC 2014) held in Copenhagen (18-23 July 2014). Title: "Predicting regional neurodegeneration using healthy functional connectome."
- Congratulations to Dr. Reza Khosrowabadi, our postdoctoral fellow. Reza has been selected to receive a trainee abstract travel award from the Organization for Human Brain Mapping (OHBM) for his abstract "Functional connectivity enhancement correlates with motor recovery after rehabilitation".
- Funding supported from BMRC TCRP grant on Multimodal connectome analysis for differentiating subtypes within early-stage dementia and mild cognitive impairment, from 04/2013-03/2016.
- Group photo during training session of MRI compatible EEG with team members of Brain Products company